AccuFlo™ Punctal Occluder

The AccuFlo™ punctal occluder is a medical device designed to occlude the punctum and thereby
provide reduction or elimination of tear drainage through the inferior or superior puncta. Each
AccuFlo™ punctal occluder is molded from silicone. The AccuFlo™ is available in four sizes (small, medium, large
and x-large). Each box contains two sterile occluders preloaded on an inserter, along with device identification
labels for use by a qualified eye care physician, and instructions for use.

AccuFlo™ Punctal Occluders are indicated for:

The AccuFlo™ is for use in patients with dry eye syndromes.

ComfortTip™ Punctal Occluder

The ComfortTip™ punctal occluder is a medical device designed to occlude the punctum and thereby
provide reduction or elimination of tear drainage through the inferior or superior puncta, thus
maintaining lubricating tears on the surface of the eye. Each ComfortTip™ punctal occluder is molded from
silicone. The ComfortTip™ is available in four sizes (x-small, small, medium, and large). Each box contains two
sterile occluders preloaded on an inserter, along with device identification labels for use by a qualified eye care
physician, and instructions for use.

ComfortTip™ Punctal Occluders are indicated for:

The ComfortTip™ is for use in patients with dry eye syndromes.

Dissolvable VisiPlug Lacrimal Plug

The Dissolvable VisiPlug® Lacrimal Plug is a temporary ophthalmic device which occludes the canaliculi to aid in the retention of natural fluid on the eye. The VisiPlug® is available in a variety of sizes to accommodate variations in anatomy and is designed to naturally dissolve over a period of 180 days.

Dissolvable VisiPlug Lacrimal Plugs are indicated for:

• To aid the determination of the potential effectiveness of occlusion therapy with non-dissolvable plugs.
• To temporarily enhance the efficacy of topical medications or ocular lubricants.
• After ocular surgery to prevent complications due to dry eyes.
• To evaluate the treatment of ocular dryness secondary to contact lens use.
• In the treatment of Dry Eye Syndrome and the dry eye components of varying ocular surface diseases.